Can external trial controls ever be trusted again?

Highlights A new statistical approach makes externally controlled single-arm trials more trustworthy by marrying two ideas: balancing covariates to mimic a randomized comparison, and modeling outcomes to guard against misspecification. The result is a doubly robust method that performs well when either the covariate balance model or the outcome model is correct, improving precision and…

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Counting crowds gets a softer, smarter nudge

Counting people in a photo isn’t just a nerdy puzzle; it’s a real‑world skein of tiny decisions: who counts, who’s occluded, where a group ends and a stray limb begins. For years, researchers trained counting systems with a blunt signal: either the count was right, or it wasn’t. But in messy scenes—dense crowds, shifting light,…

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